Protective Effect of <i>Curculigo orchioides</i> Gaertn. Extract on Heat Stress-Induced Spermatogenesis Complications in Murine Model.

orchioides extract 100 mg/kg/day (C100), 200 mg/kg/day (C200), and 400 mg/kg/day (C400) groups compared to the control group (11.401 ± 2.956 nmol/L, 11.786 ± 3.372 nmol/L, and 12.419 ± 2.618 nmol/L, respectively), but it did not reach statistical significance ( p > 0.05).

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The ultrastructure of the seminiferous tubules became abnormal after testicular heat stress, the structure of the blood–testis barrier became loose, and the Sertoli cells showed a trend of differentiation [ 48 ].

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