Monitoring of kinetics and exhaustion markers of circulating CAR-T cells as early predictive factors in patients with B-cell malignancies.

Front Immunol · 2023 · PMC10140355 · PMID 37122702

Europe PMC DOI

hedged sentences

0.0789

closest p · 1.6× alpha

0.0789

boldest claim

The sentences

showed a trendp=0.0789so close (0.05 < p ≤ 0.1)

Besides, CD8+CAR+ cells from patients receiving Axi-cel showed a trend towards a reduced proportion of a central memory phenotype as compared to patients infused with Tisa-cel (p=0.0789) ( Supplementary Figure 6B ).

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did not reach statistical significanceno p-value reported

CD4/CD8 ratio showed a reduction in CAR-T cells compared to non-modified circulating T-cells although it did not reach statistical significance.

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