Sex-dependent divergence in the effects of GLP-1 agonist exendin-4 on alcohol reinforcement and reinstatement in C57BL/6J mice.

Psychopharmacology (Berl) · 2023 · PMC10172234 · PMID 37106129

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0800

boldest claim

The sentences

near-significantp = 0.051so close (0.05 < p ≤ 0.1)

In the first hour, responding was related to exendin-4 dose [ F (2, 42) = 5.87, p = 0.006] with near-significant effects of sex [ F (2, 42) = 4.04, p = 0.051] and sex-by-dose interaction [F(2,42) = 3.09, p = 0.056].

also in 397 other papers

did not quite reach significancep = 0.056so close (0.05 < p ≤ 0.1)

4 A) revealed significant effects of exendin-4 dose [ F (2, 43) = 5.20, p = 0.01] as well as sex-by-dose interaction [ F (2, 43) = 4.87, p = 0.01], while the main effect of sex did not quite reach significance [ F (1, 43) = 3.84, p = 0.056].

also in 39 other papers

approached significancep = 0.08so close (0.05 < p ≤ 0.1)

The effect approached significance in the females ( p = 0.08), with no dose reaching significant after multiple comparison adjustments.

also in 1,232 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.