Single nucleotide polymorphisms in C-reactive protein (CRP) predict response to adjunctive celecoxib treatment of resistant bipolar depression.

Brain Behav Immun Health · 2023 · PMC10172701 · PMID 37181328

Europe PMC DOI

hedged sentences

0.0400

closest p · 0.8× alpha

0.0400

boldest claim

The sentences

nominally significantp = 0.04actually significant

When examining all subjects, nominally significant associations between carrier-status and remission (p = 0.04) and PSS-14 scores (p = 0.04) were observed after correcting for treatment arm.

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did not reach statistical significanceno p-value reported

Increased rates of HAM-D17 response (p = 0.21) and remission (p = 0.13) and lower PSS-14 scores (p = 0.13) were observed in non-carriers among subjects receiving celecoxib but they did not reach statistical significance.

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