Use of Daridorexant among Patients with Chronic Insomnia: A Retrospective Observational Analysis.

J Clin Med · 2023 · PMC10179592 · PMID 37176680

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did not reach statistical significanceno p-value reported

In prior data, there was not an increased risk of side effects at the 50 mg dose, so even though the change did not reach statistical significance, it is worth considering starting at the 50 mg dose (and/or increasing to the 50 mg dose if there is incomplete response at the lower dose) [ 25 , 26 ].

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showed a trendno p-value reported

This showed a trend toward improved effectiveness with the higher dose, but given the number of patients in this analysis, it did not meet statistical significance. 3.1.6.

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