Insulin-like growth factor 2 hypermethylation in peripheral blood leukocytes and colorectal cancer risk and prognosis: a propensity score analysis.

Front Oncol · 2023 · PMC10198613 · PMID 37213278

Europe PMC DOI

hedged sentences

0.2359

closest p · 4.7× alpha

0.2359

boldest claim

The sentences

did not reach statistical significanceP =0.2359not close (p > 0.1)

The prognostic signature was also observed in the EPIC-Italy CRC cohort, although the HR did not reach statistical significance (HR PS-adjusted , 0.69, 95% CI: 0.37 to 1.27, P =0.2359).

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a clear trendno p-value reported

Using the follow-up results of the 166 CRC patients from the EPIC-Italy cohort, we observed a clear trend for a longer OS related with IGF2 hypermethylation, although the association was not statistically significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.