However, alloSCT recipients receiving preemptive therapy showed a trend toward higher T-cell counts from day +30 to day +120 than those on letermovir prophylaxis, most markedly at day +120 [median: 235 vs. 58 CD3 + CD56 - T cells/μL, median-to-median ratio (MMR)=4.1, p=0.135, Figure 2B ].
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CD4+ T cells are the major predictor of HCMV control in allogeneic stem cell transplant recipients on letermovir prophylaxis.
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Interestingly, we also found a strong trend towards increased frequencies of CD159c + and mature CD57 + CD159c + “memory-like” NK cells in NSTR vs.