Patients receiving FTD/TPI in the third-line had a significant trend for improved PFS and OS compared to those receiving it in more advanced lines.
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RETRO-TAS, a Retrospective Observational Study of Trifluridine/Tipiracil in Chemorefractory Metastatic Colorectal Cancer.
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The rectum as the primary site of mCRC had statistically significant better PFS compared to the right colon primary and a better OS although this did not reach statistical significance.