The Role of the p16 and p53 Tumor Suppressor Proteins and Viral HPV16 E6 and E7 Oncoproteins in the Assessment of Survival in Patients with Head and Neck Cancers Associated with Human Papillomavirus Infections.

Cancers (Basel) · 2023 · PMC10216029 · PMID 37345059

Europe PMC DOI

hedged sentences

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

failed to reach statistical significancep = 0.077so close (0.05 < p ≤ 0.1)

For the oropharynx, the OS rates were 26.82% and 0% for patients who were HPV-positive and HPV-negative, respectively, although this difference failed to reach statistical significance ( p = 0.077; Figure 2 A).

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did not reach statistical significanceno p-value reported

While the results for each T stage did not reach statistical significance, there was a trend towards a higher early death risk with a higher T stage; patients with HNSCC with a T4 tumor had a 2.68-fold higher probability of death.

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