Pre-emptive TIPS for the treatment of bleeding from gastric fundal varices: Results of a randomised controlled trial.

However, actuarial probability of rebleeding-free survival did not reach statistical significance (log-rank p = 0.198; Fig. 1 A).

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• Patients treated with a pre-emptive TIPS (associated or not with collateral obliteration) had better outcome compared with those treated with standard therapy (drug therapy plus intravariceal glue injection) when analysed as per protocol, but failed to reach statistical significance on intent to treat, mainly because of the low number of patients in the study. • The improved outcomes resulted from reduced rates of rebleeding and death in patients with Child-Pugh B and C scores, because prognosis in patients with Child-Pugh A scores was good irrespective of the treatment receiv

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