Treatment of critical bone defects using calcium phosphate cement and mesoporous bioactive glass providing spatiotemporal drug delivery.

Comparing these two studies with the current one, a clear trend towards an improved scaffold handling and position stability is detectable.

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Histomorphologically, in this study an improved osseous integration of both (with/without HCM) composite scaffolds could be found and the quantitative results between the cSr and cSr-gCa(16) scaffolds showed a trend towards a smaller remaining defect width and pronounced bone formation.

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