Factor H preserves alternative complement function during ARDS, linked to improved survival.

ERJ Open Res · 2023 · PMC10291301 · PMID 37377659

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showed a trendno p-value reported

Relative factor H deficiency is associated with increased mortality during ARDS Patients with circulating factor H levels lower than the 25th percentile showed a trend toward increased probability of death in both LARMA (HR for 90-day mortality 1.36, 95% CI 0.81–2.30) and SAILS (HR for 90-day mortality 1.62, 95% CI 0.97–2.75) ( figure 5a , b).

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did not reach statistical significanceno p-value reported

The C3a:C3 ratio was higher in nonsurvivors compared to survivors, but this result did not reach statistical significance.

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