A more detailed investigation of the effect of eupatilin on cilia incidence and length in CEP290 KO RPE1 cells revealed that there was a dose response for the effect of eupatilin on cilia length and incidence ( Figure 2 H,I); 5 μM eupatilin resulted in a small increase in cilia incidence and length, which did not reach statistical significance.
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The sentences
Both OPN1MW/OPN1LW and ARR3 showed a trend for reduced expression, although not significantly, suggesting a potential effect on cones as well as rods ( Figure 5 A).