Cervical Cancer Registered in Two Developed Regions from Brazil: Upper Limit of Reachable Results from Opportunistic Screening.

For the region of Campinas, the number of cases of CIN3 and AIS registered yearly over time was compared with the cancer registries and showed a trend towards increase (121 cases in 2001 and 177 cases in 2012, p < 0.001) ( Fig. 1 , dotted line).

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There was a decreasing trend for diagnoses in the age group 45 to 64 years (from n = 143, or 44.8%, to n = 96, or 36.9%, p = 0.008) and maintained trend in age 65 years or more ( n = 83, or 26.0%, to n = 53, or 20.4%, p = 0.306) ( Fig. 2A - B ).

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There was an increasing trend for stage I diagnoses in the region of Campinas ( p = 0.033).

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The region of Campinas showed a significant trend for increased diagnoses in those patients younger than 45 years and decreased cases between 46 and 64 years, demonstrating a possible anticipation of diagnosis.

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