Umbilical cord-mesenchymal stem cells induce a memory phenotype in CD4⁺ T cells.

Even though there was no statistically significant difference, neutralization of IL-6 showed a trend toward higher T EM percentages ( Figure 7A ) and conversely lower levels of T CM ( Figure 7B ).

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Neutralizing IL-6 and TGFβ in co-cultures did not lead to a significant effect on memory formation, although especially in the case of IL-6, we found a clear trend towards a memory switch.

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