1 C) between the four groups; however, a strong trend was observed suggesting a difference in feed efficiency between WT and KO mice ( Fig. 1 D, P genotype = 0.054).
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Delta-6 desaturase (Fads2) deficiency alters triacylglycerol/fatty acid cycling in murine white adipose tissue.
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Although Atgl mRNA appeared higher in the iWAT of KO mice, it did not reach statistical significance when compared to WT mice; however, the Fads2 genotype showed a significant main effect ( P genotype = 0.01, supplemental Fig.
Lower WAT depot weight and adipocyte size in Fads2 KO mice Since we observed a highly significant main effect for genotype on body weights ( Fig. 1 B), we next examined tissue weight and adipocyte size for visceral eWAT and subcutaneous iWAT in Fads2 WT and KO mice.