Barely Significant
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PTEN is both an activator and a substrate of chaperone-mediated autophagy.

J Cell Biol · 2023 · PMC10327811 · PMID 37418003

Europe PMCDOI
2
hedged sentences
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

shy of significanceP = 0.06so close (0.05 < p ≤ 0.1)
ENO1 showed a similar trend that fell shy of significance (P = 0.06).

also in 7 other papers

nearly significantno p-value reported
A two-factor ANOVA testing for an interaction between Bafilomycin A and si Pten on LC3 flux gave an interaction term P value of 0.055, suggesting a nearly significant reduction in macroautophagy as a result of PTEN depletion ( Fig. 2 E ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.