Whole-Body Metabolism and the Musculoskeletal Impacts of Targeting Activin A and Myostatin in Severe Osteogenesis Imperfecta.

S1 ), although female oim / oim mice appeared to have lower circulating serum myostatin concentrations, which did not reach statistical significance at p < 0.05.

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The Combo treatment also increased body weights in male Wt mice (+8.9%, p = 0.003), male oim/oim mice (+14.1%, p < 0.001), and female oim/oim mice (+7.8%, p = 0.022) but failed to reach statistical significance in female Wt mice.

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