However, these results did not reach statistical significance, which may require a larger sample size (Baro et al., 2022 ).
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Neuroimmunomodulation of vagus nerve stimulation and the therapeutic implications.
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taVNS showed a trend of decreased weight gain, improved sucrose preference, increased mechanical withdrawal threshold, and suppression of elevated TNF-α levels in rats with depression and chronic somatic pain (Guo et al., 2020 ).