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Gastric vagal afferent signaling to the basolateral amygdala mediates anxiety-like behaviors in experimental colitis mice.

JCI Insight · 2023 · PMC10371239 · PMID 37200091

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Although there was a trend toward less time spent in the closed arms in CNO-DSS group compared with saline-DSS group, the difference did not reach statistical significance ( Figure 7I ).

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An unexpected finding of this study was that, although GV and SAP reduced anxious phenotypes as revealed using the EPM, LDB and NSF tests, the effect of vagal deafferentation on the OF test failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.