Following the second BNT162b2 dose, we showed a trend for the enrichment of CD27+IgM− memory RBD-specific B cells, which are known to correlate with a strong humoral response upon re-challenge.
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Receptor-Binding-Domain-Specific B Cell Responses Induced by mRNA Immunization against SARS-CoV-2.
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The sentences
The increase in CD19+CD27+IgM− memory B cells did not reach statistical significance, probably due to the small study size.