Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.

Nat Commun · 2023 · PMC10404286 · PMID 37543677

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0.0876

closest p · 1.8× alpha

0.0876

boldest claim

The sentences

did not reach statistical significanceP = 0.0876so close (0.05 < p ≤ 0.1)

Next, we could confirm significant upregulation of YAP target genes, including cellular communication network factor 1 ( Ccn1 ), connective tissue growth factor ( Ctgf ), the Rab effector synaptotagmin like 2 ( Sytl2 ), and a slight increase of insulin-like growth factor I receptor ( Igf1r ) that did not reach statistical significance (P = 0.0876) by qPCR (Fig. 6D ).

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showed a trendno p-value reported

Although several genes showed a trend towards being induced in Arid1a icKO infarct areas (Fig. 7F and Supplemental Fig. 6G ), none of them were significantly changed (two-way ANOVA with Šídák’s multiple comparisons test).

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