Reduction of brain stem pathology and transient amelioration of early cognitive symptoms in transgenic mice treated with a monoclonal antibody against α-synuclein oligomers/protofibrils.

Aging Brain · 2023 · PMC10407822 · PMID 37559953

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hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

1 I, middle panel), but the difference did not reach statistical significance (Mann-Whitney U test p = 0.10, U = 16, Z = −1.6).

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showed a trendno p-value reported

In the prefrontal cortex the number of pS129 α-syn deposits showed a trend towards reduction after mAb47 treatment ( Fig. 1 I, middle panel), but the difference did not reach statistical significance (Mann-Whitney U test p = 0.10, U = 16, Z = −1.6).

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