Spatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer.

Nat Commun · 2023 · PMC10409784 · PMID 37553345

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did not reach statistical significanceno p-value reported

In the HGIN progression samples, the mean IHC score value of TAGLN2 exhibited an increase in the after-progression group compared to the before-progression group, although it did not reach statistical significance due to the limited sample size (Fig. 6b–d ).

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a clear trendno p-value reported

Notably, a clear trend was observed, with higher grades of dysplasia associated with a significantly increased risk of developing ESCC.

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