Response to SARS-CoV-2 initial series and additional dose vaccine in pediatric patients with predominantly antibody deficiency.

Front Immunol · 2023 · PMC10413262 · PMID 37575247

Europe PMC DOI

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0.0510

closest p · 1.0× alpha

0.1500

boldest claim

The sentences

a strong trendp=0.051so close (0.05 < p ≤ 0.1)

Finally, pediatric patients with secondary PAD had a strong trend toward a lower mean anti-spike antibody response after two-dose vaccine series compared to primary PAD patients (767.1 vs. 3,679.2 U/mL; p=0.051) ( Figure 2 ).

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did not reach statistical significancep=0.15not close (p > 0.1)

After a third-dose of SARS-CoV-2 vaccine, anti-spike antibody levels in patients receiving IgRT trended lower than those that did not receive IgRT, although this did not reach statistical significance (13,893.5 vs. 24,017.6 U/mL; p=0.15) ( Supplemental Figure 2 ).

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