An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection.

Front Immunol · 2023 · PMC10436000 · PMID 37600784

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closest p · 1.0× alpha

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showed a trendP > 0.05actually significant

Analyses of CD8 + T cells showed a trend towards increased single IFN-γ and dual cytokine expression in the BoHV-4-M-NSP5 prime-boost group over time ( P > 0.05; Figures 3D, E ).

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a marked trendno p-value reported

However, the BoHV-4-M-NSP5 prime-boost vaccination showed a marked trend toward reduced lung pathology following PRRSV-1 challenge.

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