Circulating Vitamin D Level and Risk of Sudden Cardiac Death and Cardiovascular Mortality: A Dose-Response Meta-Analysis of Prospective Studies.

J Korean Med Sci · 2023 · PMC10442497 · PMID 37605499

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showed a trendno p-value reported

Our dose-response analysis showed a trend of inverse association between circulating 25(OH)D and risk of SCD and CVD mortality ( P for nonlinearity < 0.01, reference = 100 nmol/L) ( Fig. 5A ).

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a strong trendno p-value reported

The sub-analysis of studies by population with and without pre-existing comorbidities revealed a strong trend toward a greater risk increase of SCD and CVD mortality among general population compared with populations with pre-existing CVD or CKD with 85%, 75%, and 81% increased risk in each group respectively.

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