Barely Significant
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Sexually Transmitted Infections in 2000-2018 in a Specialised Centre: Comparison between Pre-Crisis, Crisis, and Post-Crisis Period.

J Clin Med · 2023 · PMC10455687 · PMID 37629296

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a clear trendno p-value reported
However, there was a clear trend towards a progressive increase in these infections from 2000 to 2018, which could be explained by the improvement in screening systems.

also in 19,460 other papers

showed a trendno p-value reported
The evolution of the number of positive diagnoses during the entire study period showed a trend of progressive increase in Sexually Transmitted Infections from 2000 to 2018.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.