Association between Chinese herbal medicine (CHM) treatment and depression among cancer patients in China: An outpatient-based cross-sectional study.

Although the full adjustment of confounders (gender, medical insurance, ECOG PS, cancer stage, gene mutation, metastasis at diagnosis, time since diagnosis, treatment plan at visit) did not reach statistical significance ( P > .05), the OR remained consistent, indicating a stable relationship between CHM treatment and depression status.

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After adjusting for potential confounders such as ECOG PS, cancer stage, gene mutation, metastasis at diagnosis, time since diagnosis, and treatment plan at visit, the odds ratio (OR) for CHM treatment was less than 1 ( P < .05), and the OR for the duration of CHM treatment gradually decreased, with a significant trend ( P for trend < .05).

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