Sprague Dawley rats from different vendors vary in the modulation of prepulse inhibition of startle (PPI) by dopamine, acetylcholine, and glutamate drugs.

Psychopharmacology (Berl) · 2023 · PMC10471717 · PMID 37580441

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0.0670

closest p · 1.3× alpha

0.0700

boldest claim

The sentences

near-significantp =0.067so close (0.05 < p ≤ 0.1)

PPI was generally lower in the Envigo rats compared to the CR rats with significant vendor effects as sexes-combined ( F 1,36 =15, p =0.0004) and in the females ( F 1,22 =12, p =0.002), with a near-significant effect in the males ( p =0.067).

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showed a trendp =0.07so close (0.05 < p ≤ 0.1)

The female rats showed a trend toward a vendor by apomorphine interaction ( p =0.07).

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