Previous radiotherapy improves treatment responses and causes a trend toward longer time to progression among patients with immune checkpoint inhibitor-related adverse events.

Cancer Immunol Immunother · 2023 · PMC10491510 · PMID 37486396

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showed a trendno p-value reported

In this fairly large, multicenter retrospective study, we found that previous RT increased response rates and showed a trend toward improved TTP in ICI-treated patients.

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did not reach statistical significanceno p-value reported

There was a significantly longer time to progression (TTP) in the RT + /AE + group compared to the RT −/AE − and RT + /AE − groups (log rank p = 0.001 and p < 0.001, respectively), but the trend toward longer TTP in the RT + /AE + group did not reach statistical significance in pairwise comparison to that in the RT −/AE + group.

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