Neoadjuvant treatment does not influence PD-L1 expression in stage III non-small-cell lung cancer: a retrospective analysis of tumor samples from the trials SAKK 16/96, 16/00, 16/01, and 16/14.

ESMO Open · 2023 · PMC10515281 · PMID 37441877

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showed a trendno p-value reported

17 This study also included an RT-free cohort, whose tumor samples showed a trend for an upregulation of PD-L1 TPS after neoadjuvant treatment.

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did not reach statistical significanceno p-value reported

For both OS and EFS, upregulation of PD-L1 TPS after neoadjuvant treatment correlated with better patient outcomes, but the difference did not reach statistical significance ( Figure 4 A and B).

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