The immune microenvironment characterisation and dynamics in hormone receptor-positive breast cancer before and after neoadjuvant endocrine therapy.

Cancer Med · 2023 · PMC10524081 · PMID 37553911

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0880

boldest claim

The sentences

a trend towards significancep = 0.08so close (0.05 < p ≤ 0.1)

In this study, sTIL infiltration decreased by a median 1% during NET, with a trend towards significance ( p = 0.08).

also in 2,760 other papers

showed a trendp = 0.088so close (0.05 < p ≤ 0.1)

An increase in PD‐L1 expression after NET showed a trend towards significant ( p = 0.088) and CD‐4+ T cells significantly increased after NET ( p = 0.03).

also in 53,322 other papers

a significant trendno p-value reported

52 On the contrary, another study comparing NET durations of 4, 8 or 12 months showed a significant trend for higher pCR rates with longer NETs. 53 There are also difficulties in evaluating the NET response.

also in 9,775 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.