showed a trendp = 0.30
Furthermore, genetic effects in the Knight-ADRC individuals showed a trend in the same direction as in EMIF/ADNI with a genetic correlation of 0.42 (95% CI [− 0.46; 1.00], p = 0.30) between discovery and replication.
Furthermore, genetic effects in the Knight-ADRC individuals showed a trend in the same direction as in EMIF/ADNI with a genetic correlation of 0.42 (95% CI [− 0.46; 1.00], p = 0.30) between discovery and replication.
In total, weights for 13,420 transcripts with nominally significant heritability estimates were available.
Mediation analyses Our main GWAS main analyses identified several loci showing highly significant association with the biomarker PCs defined for this study.