Immunoblot analysis of ETC complexes showed a strong trend toward reductions in complexes I-IV with HC3 and RSM ( Fig 4B ), though only changes in complex I was significantly different ( S5A Fig ).
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Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.
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Over the course of the 10-week infection, RSM treatment resulted in significantly increased fecal egg burden specifically at week 8 but showed a trend at all other time points ( S9B Fig ).