Off-the-shelf CAR-engineered natural killer cells targeting FLT3 enhance killing of acute myeloid leukemia.

In addition, compared with sIL-15 NK cells, FLT3 CAR_sIL-15 NK cells were significantly increased in the BM ( Figure 6 C; supplemental Figure 7 B) and showed a trend of increase in the PB, although the difference did not reach statistical significance ( Figure 6 D; supplemental Figure 7 C).

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