Barely Significant
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Clinicopathological characteristics, evolution, treatment pattern and outcomes of hormone-receptor-positive/HER2-low metastatic breast cancer.

Front Endocrinol (Lausanne) · 2023 · PMC10595148 · PMID 37881502

2
hedged sentences
0.0670
closest p · 1.3× alpha
0.0670
boldest claim

The sentences

near-significantp=0.067so close (0.05 < p ≤ 0.1)
Without capecitabine, the PFS was 9.30 months for HER2-zero and 7.95 months for HER2-low, a near-significant difference (p=0.067, HR 0.821, 95% CI 0.665-1.014, Figure 5D ).

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Variations were observed in PFS among different patterns of HER2 evolution during 1st-2nd line endocrine therapy; however, these differences did not reach statistical significance (HER2-zero to HER2-zero vs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.