BnpC showed a trend of increasing estimated number of clusters when the true number of clusters increased and was accurate when the underlying number of clusters was small (4 and 8).
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Assessing the performance of methods for cell clustering from single-cell DNA sequencing data.
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For the experiment of varying number of mutation, we noticed an increasing trend for SCG, SCClone, BnpC and RobustClone’s V-measure when the number of mutations increased, whereas SCITE showed a reverse trend ( Fig 5 ).
SCITE’s running time did not show a clear trend, and it ranged between 800s and 1600s.