Despite a marked trend towards decreased O 2 in dead animals, their tumour areas produced phosphorescence lifetime values between 44 and 47 μs, which corresponded to hypoxic tissue with 5–20 μM O 2 .
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Analysis of tumour oxygenation in model animals on a phosphorescence lifetime based macro-imager.
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And on Days 3 and 4 of the Main and Preliminary Trials, when tumours were not palpable, O 2 showed a positive trend compared to Days 7 and 10, but were still lower than on Day 17 (Fig. 2 B).
At the same time, ANOVA test showed a trend towards increased LT values in the euthanised vs live animals (see statistical details in Fig. 2 C).