Statin Use and Coronary Artery Calcification: a Systematic Review and Meta-analysis of Observational Studies and Randomized Controlled Trials.

Curr Atheroscler Rep · 2023 · PMC10618336 · PMID 37796384

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showed a trendno p-value reported

Although the effect modification of follow-up time on the results from RCTs did not reach the statistical significance in both subgroup and meta-regression analysis, both analyses showed a trend toward smaller effect sizes as the follow-up was prolonged (range of 1–2 years) which aligns with our expectations.

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did not reach statistical significanceno p-value reported

Meta-analyses of RCTs did not reach statistical significance; however, the pooled effects differed significantly depending on whether CAC was quantified as Agatston score or volume.

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