Burden of elevated lipoprotein(a) among patients with atherosclerotic cardiovascular disease: Evidence from a systematic literature review and feasibility assessment of meta-analysis

PLoS One · 2023 · PMC10659166

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did not reach statistical significanceno p-value reported

Additionally, three of the seven studies reported numerically higher all-cause mortality events percentage in patients with elevated Lp(a) levels; however, the results did not reach statistical significance [ 31 , 34 , 43 ].

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showed a trendno p-value reported

Three of the 16 studies reporting HRs from multivariate analyses showed a trend for association between elevated Lp(a) levels and MACE vs low Lp(a) levels; however, the association was not significant ( Fig 2A ) [ 22 , 24 , 30 ].

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an increasing trendno p-value reported

Two studies did not report significant results or show an increasing trend for association [ 14 , 43 ].

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