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Immunologic and Genetic Contributors to CD46-Dependent Immune Dysregulation.

J Clin Immunol · 2023 · PMC10661731 · PMID 37477760

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showed a trendno p-value reported
T cells of mutation carriers showed a trend to produce equal or more pro-inflammatory cytokines (IL-6, IFN-γ, TNF-α) following T cell receptor ligation plus CD28 co-stimulation compared to controls (Supplemental Figure 4 ), although these data did not reach statistical significance.

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