Targeting Pro-Oxidant Iron with Exogenously Administered Apotransferrin Provides Benefits Associated with Changes in Crucial Cellular Iron Gate Protein TfR in a Model of Intracerebral Hemorrhagic Stroke in Mice.

Antioxidants (Basel) · 2023 · PMC10669272 · PMID 38001798

Europe PMC DOI

hedged sentences

0.0624

closest p · 1.2× alpha

0.0624

boldest claim

The sentences

showed a trendp = 0.0624so close (0.05 < p ≤ 0.1)

Nonetheless, GPX4 mRNA levels showed a trend of being lower in the ipsilateral hemisphere of the ICH mice when compared with sham animals ( p = 0.0624 in ICH-vehicle and p = 0.0681 in ICH-hATf mice) ( Figure 6 ).

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did not reach statistical significanceno p-value reported

ICH increased system xc- gene expression (Slc3a2 mRNA) irrespective of the treatment; at the protein level (xCT), it did not reach statistical significance ( Figure 6 ).

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