Further Association of Germline CHEK2 Loss-of-Function Variants with Testicular Germ Cell Tumors

J Clin Med · 2023 · PMC10672725

Europe PMC

hedged sentences

0.2315

closest p · 4.6× alpha

0.2315

boldest claim

The sentences

borderline significancep = 0.2315not close (p > 0.1)

However, this finding reached only borderline significance ( p = 0.2315).

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did not reach statistical significanceno p-value reported

However, we did observe a trend, which did not reach statistical significance, towards an association with seminomas and aggressive TGCTs.

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showed a trendno p-value reported

Similarly, individuals with CHEK2 LOF in this study also showed a trend, which did not, however, reach statistical significance, towards an earlier age of onset (5.67 years; 29.5 vs. 35.17; p = 0.2315; Table 3 ).

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