High cell-free DNA is associated with disease progression, inflammasome activation and elevated levels of inflammasome-related cytokine IL-18 in patients with myelofibrosis.

Front Immunol · 2023 · PMC10687201 · PMID 38035089

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did not reach statistical significanceno p-value reported

Although JAK2 V617F-positive patients released moderately higher IL-18 levels than JAK2 V617F-negative ones, differences did not reach statistical significance ( Figure 3B ).

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showed a trendno p-value reported

Monocyte counts were higher in patients and showed a trend towards correlation with IL-18 levels, suggesting monocytes represent a source of circulating IL-18.

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