The effect of adjuvant chemotherapy on survival in node negative colorectal cancer with or without perineural invasion: a systematic review and meta-analysis.

Front Surg · 2023 · PMC10687374 · PMID 38033531

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

For PNI- patients, ACT also showed a trend towards improved DSS over observation that did not reach statistical significance (HR 0.76, 95% CI 0.57–1.00).

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