Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner.

As noted by the reviewer there was indeed a highly significant effect of the GRK2/3 inhibitor compound 101 and this is now also noted in Figure 2D and its associated legend.

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Moreover, pre-addition of the hFFAR2 antagonist/inverse agonist CATPB not only prevented the MOMBA-induced enhanced detection of the receptor protein by the pSer 296 /pSer 297 antiserum but showed a trend to reduce this below basal levels ( Figure 4A ) although this did not reach statistical significance ( Figure 4B ).

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