Regarding predictors for amputation, beside elevated myoglobin levels and renal insufficiency, interestingly, combined arterial and venous injury of the popliteal area showed a trend towards higher amputation rates.
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The Mangled Extremity Severity Score (MESS) does not predict amputation in popliteal artery injury.
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The sentences
Two other factors, namely concomitant venous trauma and classification of ischemia severity showed a statistical trend to correlate with amputation, yet did not reach statistical significance at p values of 0.0591 and 0.0638, respectively.