The relationship between sleep, gut microbiota, and metabolome in patients with depression and anxiety: A secondary analysis of the observational study.

Comparison of bacterial composition between the groups At the family level, Ruminococcaceae showed a trend-toward higher prevalence in the insomnia group compared to the non-insomnia group, and conversely, Bifidobacteriaceae showed a trend-toward higher prevalence in the non-insomnia group compared to the insomnia group ( Fig 3 ).

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However, these differences did not reach statistical significance after the FDR correction.

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