A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma.

In both the stroma and the tumor areas, a clear trend emerged toward lower infiltration for all the immune cell populations in the PODO447 high group (except for CD20 + cells in tumor-rich areas).

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Interestingly, despite this absence of PODO447 tumor H-score modulation, in all three cohorts (A, B, C) the proportion of tumors that are PODO447 positive and the median PODO447 tumor H-score are slightly higher in patients that previously received chemotherapy, although this trend did not reach statistical significance ( Table 2 ).

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